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Figure 1. CE-SDS virtual gel output (LabChip GXII) for monoclonal antibody to FABP3, clone 8H9 under non-reduced (NR, left) and reduced (R, right) conditions.
HPLC analytical SEC for final product
Figure 2. Analytical SEC of final product.
HPLC analytical SEC after 3 freeze-thaw cycles
Figure 3. HPLC analytical SEC after 3 freeze-thaw cycles.
Octet binding analysis
Figure 4. Octet BLI analysis, antibody was loaded on sensor for capture of FABP3 protein in different concentrations.(for reference only; data shown are from a single production batch at release and may not be representative of other batches)
Catalogue #
R1-272-100
Name
Monoclonal antibody to FABP3, clone 8H9, hIgG1
Target
FABP3
Target Description
Recombinant human FABP3 protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line.
Alternative Names
Fatty acid binding protein 3, Heart-FABP, heart-type fatty acid binding protein, hFABP, MDGI, mammary-derived growth-inhibitor
Uniprot ID
P05413
Clonality
Human monoclonal
Clone
8H9
Class
hIgG1
Reactivity
Binds to human FABP3. Lack of cross-reactivity to FABP7, FABP4, PMP2, FABP9, FABP12, and FABP5 proteins was confirmed using an Octet system.
Application
ELISA
Protocol
Concentration
1 mg/ml
Buffer
PBS, pH 7.4, Proclin 0.05%
Shipping
Shipped with blue ice.
Storage
Store at +2 °C to +8 °C.
Background
Fatty acid binding protein 3 (FABP3) is a small (15 kDa) cytoplasmic protein that is expressed in various tissues, including the heart and skeletal muscle. It belongs to the family of fatty acid binding proteins (FABPs) and plays a crucial role in the metabolism of fatty acids by binding to and transporting long-chain fatty acids to the mitochondria for β-oxidation or storage. FABP3 has been identified as a promising biomarker for several cardiovascular diseases, including acute myocardial infarction (AMI) and heart failure. In cases of AMI, the rapid increase of FABP3 levels in the bloodstream establishes it as an excellent early diagnostic marker. Similarly, elevated levels of FABP3 have been observed in patients with heart failure, suggesting that it could be used as a prognostic marker.
This product is for research use only
TECHNICAL ASSISTANCE
Please refer any technical questions to
technical.support@icosagen.com
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