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Figure 1. CE-SDS virtual gel output (LabChip GX) for monoclonal antibody to FGF-21, clone 12E12 under non-reduced (NR, left) and reduced (R, right) conditions.
Figure 2. Analytical SEC of final product.
Figure 3. HPLC analytical SEC after 3 freeze-thaw cycles.
Figure 4. Octet BLI analysis, antibody was loaded on sensor for capture of FGF-21 protein in different concentrations.(for reference only; data shown are from a single production batch at release and may not be representative of other batches)
Catalogue #
R1-232-100
Name
Monoclonal antibody to FGF-21, clone 12E12, hIgG1
Target
Recombinant FGF-21 protein
Target Description
Recombinant FGF-21 protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line.
Alternative Names
FGF21, fibroblast growth factor 21
Uniprot ID
Q9NSA1
Source
Human
Clonality
Human monoclonal
Clone
12E12
Class
hIgG1
Reactivity
Binds to FGF-21 protein. Lack of cross-reactivity to FGF19 and FGF23 was demonstrated with ELISA.
Application
ELISA
Protocol
Concentration
1 mg/ml
Buffer
PBS, pH 7.4
Related Products
No established recommended antibody pairing for this clone.
Shipping
Shipped on dry ice.
Storage
Store in -65...-85 °C. Avoid multiple freeze-thaw cycles.
Background
Fibroblast growth factor 21 (FGF21) is a protein hormone synthesized mainly in the liver. It regulates glycose and lipid metabolism and contributes to the energy balance. FGF21 has been suggested as a promising biomarker for several diseases like non-alcoholic fatty liver disease (NAFLD), heart failure, obesity, type II diabetes, diabetic nephropathy, renal disease, mitochondrial disease, and others. FGF21-based therapies are under development for non-alcoholic steatohepatitis (NASH) and related metabolic diseases.
This product is for research use only
TECHNICAL ASSISTANCE
Please refer any technical questions to
technical.support@icosagen.com
© 2026 Icosagen
