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Figure 1. CE-SDS virtual gel output (LabChip GXII) for monoclonal antibody to Leptin, clone 6F7 under non-reduced (NR, left) and reduced (R, right) conditions.
Figure 4. Octet BLI analysis, antibody was loaded on sensor for capture of Leptin protein in different concentrations.(for reference only; data shown are from a single production batch at release and may not be representative of other batches)
Catalogue #
R1-281-100
Name
Monoclonal antibody to Leptin, clone 6F7, hIgG1
Target
Recombinant leptin protein
Target Description
Recombinant Leptin protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line.
Alternative Names
LEPD, OB, OBS
Uniprot ID
P41159
Clonality
Human monoclonal
Clone
6F7
Class
hIgG1
Reactivity
Binds to Leptin protein
Application
ELISA, CLIA
Protocol
Concentration
1 mg/ml
Buffer
PBS, pH 7.4, Proclin 0.05%
Related Products
Leptin antibody clone 6F7 has been identified as a recommended detection antibody with clone 2B3 (cat# R1-280-100). The antibody pair 2B3-6F7 was additionally validated in human serum.
Shipping
Shipping on blue ice.
Storage
Store at +2 °C to +8 °C.
Background
Leptin is a 16 kDa protein hormone mainly secreted from the adipose tissue. Its main function is to bind with receptors in the hypothalamus which results in suppression of hunger, stimulation of satiety and increase in energy expenditure. In addition to its role in energy homeostasis, leptin is involved in various physiological processes, including reproduction, immunity, and bone metabolism. Leptin might serve as a novel biomarker since it is associated with diseases such as obesity, cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), and neurodegenerative diseases.
This product is for research use only
TECHNICAL ASSISTANCE
Please refer any technical questions to
technical.support@icosagen.com