Monoclonal antibody to RBP4, clone 11A6, hIgG1

Catalogue #

R1-652-100

Name

Monoclonal antibody to RBP4, clone 11A6, hIgG1

Target

Recombinant RBP4-His protein

Target Description

Recombinant RBP4 protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line.

Alternative Names

Retinol binding protein 4, plasma retinol-binding protein, PRBP

Uniprot ID

P02753

Clonality

Human monoclonal

Clone

11A6

Class

hIgG1

Reactivity

Binds to RBP4 protein.

Dissociation constant (K_D)

Summary of antibody screening to soluble RBP4 using an Octet system.
KD, M: 2,41E-10

Application

ELISA, CLIA

Protocol

Purification

Protein A affinity chromatography followed by gel filtration

Purity

>90%

Concentration

1 mg/ml

Buffer

PBS pH 7.4

QC

Simply Blue Safe stained SDS-PAGE, analytical HPLC-SEC, Octet binding.

Related Products

RBP4 antibody clone 11A6 has been identified as a recommended capture antibody with clone 14D5 (cat# R1-653-100). In our in-house testing, the pair recognized native RBP4 purified from human plasma both as a free form and in a complex with prealbumin.

Shipping

Shipped on dry ice.

Storage

Store at -20 °C to -70 °C. Avoid multiple freeze-thaw cycles.

Background

Retinol binding protein 4 (RBP4) is a plasma retinol (Vitamin A) transporter that carries retinol from the liver to the periphery. Changes in RBP4 levels are connected to a wide range of metabolic diseases, including obesity, insulin resistance (IR), metabolic syndrome, type 2 diabetes (T2D), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver (NAFL), cardiovascular diseases, and others.