Mouse monoclonal antibody to human Artemin (clone 1F3)

Catalogue #

325-100

Name

Mouse monoclonal antibody to human Artemin (clone 1F3)

Target

Human Artemin

Target Description

Recombinant human Artemin protein produced using CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purified from cell culture supernatant

Alternative Names

Enovin, Neublastin, ARTN, EVN

Uniprot ID

Q5T4W7

Clonality

Mouse monoclonal

Clone

1F3

Class

mIgG1

Reactivity

Human Artemin

Application

ELISA, IF, IHC

Protocol

ELISA:

0,1-1 µg/ml

IF:

0,3-20 µg/ml

IHC:

5 µg/ml

Purification

Protein G affinity chromatography followed by desalting.

Concentration

1 mg/ml

Buffer

PBS pH 7.4, with 0.1% sodium azide

QC

SDS-PAGE, analytical HPLC-SEC, ELISA

Shipping

Shipping in ambient conditions.

Storage

Store at -20 °C to -70 °C. Avoid multiple freeze-thaw cycles.

Background

Artemin supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex (UniProt)