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Figure 1. Western Blot analysis of RNase 7 antibody 4C4. Human RNase 7 was expressed by CHOEBNALT85 cell line. 10 µl of cell culture supernatant was loaded per lane. Lane 1 non-reduced conditions; Lane 2 Reduced conditions; Lane 3 Prestained Protein Ladder, Naxo 8003
(for reference only; data shown are from a single production batch at release and may not be representative of other batches)
Catalogue #
407-100
Name
Mouse monoclonal antibody to human Ribonuclease 7 (clone 4C4)
Target
Human Ribonuclease 7
Target Description
Recombinant human RNase 7 protein produced by CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line
Alternative Names
RNase 7, SAP-2, skin-derived antimicrobial protein 2, RNAS7
Uniprot ID
Q9H1E1
Clonality
Mouse monoclonal
Clone
4C4
Class
mIgG1
Reactivity
Human Ribonuclease7
Application
ELISA, WB, IHC, IF
Protocol
Concentration
1 mg/ml
Buffer
PBS pH 7.4, with 0.1% sodium azide
Shipping
Shipping in ambient conditions.
Storage
Store at -20 °C to -70 °C. Avoid multiple freeze-thaw cycles.
Background
RNase 7 exhibit potent ribonuclease activity and thus may contribute to the well-known ribonuclease activity of human skin. RNase 7 revealed broad spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nm) against a vancomycin-resistant Enterococcus faecium (Harder and Schröder, 2002)
References
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This product is for research use only
TECHNICAL ASSISTANCE
Please refer any technical questions to
technical.support@icosagen.com