Mouse monoclonal antibody to MLV p30 (clone 4B2)

Catalogue #

A2-301-100

Name

Mouse monoclonal antibody to MLV p30 (clone 4B2)

Target

MLV p30

Target Description

Full length recombinant MLV-Gag p30 capside protein, produced in E. coli

Alternative Names

Murine Leukemia Virus p30 protein, Murine Leukemia Virus Capsid Protein

Clonality

Mouse monoclonal

Clone

4B2

Class

mIgG1

Reactivity

MLV Gag, p30

Application

ELISA, WB

Protocol

ELISA:

0,05-0,1 µg/ml

WB:

0,5 µg/ml

Purification

Protein G affinity chromatography

Buffer

PBS pH 7.4, 0.1% sodium azide

Shipping

Shipping in ambient conditions.

Storage

Store at -20 °C to -70 °C. Avoid multiple freeze-thaw cycles.

Background

Murine leukemia viruses belong to family of Retroviruses group and are named for their ability to cause cancer in mice. Some form of MLV’s are used in cancer research. The retroviral Gag protein plays important roles at several stages in the viral life cycle. Late in infection, the Gag precursor protein acts to mediate the assembly and release of virion particles. After budding, the core matures by cleavage of Gag precursor protein into the mature core proteins, the matrix (MA), capsid (CA) and nucleocapsid proteins. These separated Gag proteins then play roles in the early stages of infection